Disegno di Infrastrutture e Opere Civili
- Docente: FRANCESCA PICCHIO
- Docente: ANNA SANSEVERINO
Disegno di Infrastrutture e Opere Civili
Il corso ha lo scopo di fornire gli elementi e le nozioni di base delle piu moderne e aggiornate tecnologie multiomiche utilizzate in campo farmacologico per l'identificazione di nuovi target farmacologici e il seguente sviluppo di molecole suscettibile di divenire farmaci.
Caratteristiche, principi fisici di funzionamento ed esempi dei moderni rivelatori di particelle utilizzati in fisica nucleare e subnucleare e in altri campi.
The first part of the course is dedicated to a simulation code which transports neutrons, photons and electrons, as well as charged particles. There will be a series of practical lessons, after a brief theoretical introduction, in which the students will learn to create an input file and to simulate transport problems. At the end of this first part, the students will be able to create geometries, to set the physics, to make requests to the program and to analyze the results from a statistical point of view. The second part of the course is dedicated to the modelization and simulation of radiation-induced biological effects at the sub-cellular/cellular level and at the level of tissues and organs. The attention will be focused on chromosome aberrations and their consequences in terms of cell death or cell conversion to malignancy, as well as the modelization of such effects at the tissue/organ level, with examples of applications in hadrontherapy and space radiation protection.
Corso già attivo negli anni scorsi con il titolo "Structural Biology and Pharmacology", adesso abbreviato in "Structural Biology"
In the first part, the course will cover the fundamentals of statistics applied to biology, with an additional focus on those methods deemed essential in big data analysis.
In the second part, the course will focus on computational tools, methods and environments used in big data analysis.
Corso opzionale (6 crediti-48 ore) per il primo anno del curriculum MOLECULAR AND DIGITAL BIOLOGY (MDB).
Optional course (6 credits-48 hours) for the 1st year of the curriculum MOLECULAR AND DIGITAL BIOLOGY (MDB).
This course provides a solid foundation in Molecular Biology that is essential for the more advanced courses in this master program. Students will learn key processes such as DNA replication, transcription and translation both in prokaryotes and eukaryotes. Moreover, students will acquire knowledge in basic techniques of nucleic acids manipulation for cloning, library screening and recombinant protein expression.
Cod. 510328 - 6 CFU
Lessons: 48 hours
Microbial world: structure, and functions of prokaryotic cells. Microbial metabolism and biosynthesis. Microbial growth (dynamics), environmental effects on growth and cultivation. Antibiotics and microbial growth. Essential virology: the nature of viruses and overview of the viral replication cycle. Genome plasticity. Regulation of gene expression. Gene transfer. Mechanism of microbial evolution. Microbial phylogeny and classification systems. Metabolic and ecological diversity of bacteria. Archaea: overview of the principal groups.
Madigan, Bender, Buckley, Sattley, Stahl. Brock Biology of Microrganisms. XVI edition. Pearson, 2022.
Joanne Willey, Kathleen Sandman and Dorothy Wood. 2023. Prescott's Microbiology, 12th Edition, McGraw Hill.
Cod. 510328 - 6 CFU
Lessons: 48 hours
Microbial world: structure, and functions of prokaryotic cells. Microbial metabolism and biosynthesis. Microbial growth (dynamics), environmental effects on growth and cultivation. Antibiotics and microbial growth. Essential virology: the nature of viruses and overview of the viral replication cycle. Genome plasticity. Regulation of gene expression. Gene transfer. Mechanism of microbial evolution. Microbial phylogeny and classification systems. Metabolic and ecological diversity of bacteria. Archaea: overview of the principal groups.
SUGGESTED TEXTBOOKS:
Madigan, Bender, Buckley, Sattley, Stahl. Brock Biology of Microrganisms. XVI edition. Pearson, 2022.
Joanne Willey, Kathleen Sandman and Dorothy Wood. 2023. Prescott's Microbiology, 12th Edition, McGraw Hill